Rangachari, Manu
Biography
I grew up in Hamilton, Ontario, and received an Honours Bachelor of Arts and Science degree from McMaster University in Hamilton, before starting a Ph.D. at the University of Toronto under the supervision of Josef Penninger. I investigated the role of the immunoregulatory molecules T-bet and Cbl-b in the pathogenesis of murine experimental autoimmune myocarditis (EAM). I had the good fortune of completing my Ph.D. studies in the gorgeous imperial city of Vienna when Josef moved his lab there in 2003. I defended my Ph.D. at the University of Toronto in December 2006. I believe that an important goal of modern biology is to shed light and insight on the mechanisms of disease, with the ultimate aim of alleviating human suffering. The Center for Neurologic Disease, and the Kuchroo lab in particular, is an excellent place to pursue these interests. I am investigating the role of costimulatory signaling pathways in both T cell biology and the pathogenesis of EAE. I am also developing a mouse model of antigen-specific diabetes induction.
Outside of the lab, my interests include reading for pleasure, Netflix, and having my heart broken every spring by my Toronto Maple Leafs.
Published Work
1989. Worldly reflections. Hamilton, Ont. : M. Rangachari. (Poetry)
